Cramp1 | cramped chromatin regulator 1

GeneMGI:1930190Synonyms: 5830477H08Rik, Tce4, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Embryo Growth/size/body region Digestive/alimentary Nervous system Skeleton Mortality/aging Craniofacial

13 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition3 supporting datasetsCramp1em1(IMPC)BayheterozygoteEarly adult3.98x10-5 
abnormal embryo size1 supporting datasetCramp1em1(IMPC)BayhomozygoteE12.5N/A * 
increased bone mineral content2 supporting datasetsCramp1em1(IMPC)BayheterozygoteEarly adult3.63x10-11 
abnormal placenta size1 supporting datasetCramp1em1(IMPC)BayhomozygoteE12.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsCramp1em1(IMPC)BayhomozygoteEarly adultN/A * 
cleft palate1 supporting datasetCramp1em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal bone structure1 supporting datasetCramp1em1(IMPC)BayheterozygoteEarly adult1.61x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cramp1em1(IMPC)BayExon Deletionmouse
Cramp1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cramp1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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