Prdm15 | PR domain containing 15

GeneMGI:1930121Synonyms: E130018M06Rik, Zfp298

Physiological systems

4 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Mortality/aging Cardiovascular system

2 No significant impact

20 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

increased heart left ventricle size1 supporting datasetPrdm15tm1b(EUCOMM)WtsiheterozygoteEarly adult4.51x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetPrdm15tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
thick ventricular wall1 supporting datasetPrdm15tm1b(EUCOMM)WtsiheterozygoteEarly adult4.35x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prdm15tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Prdm15tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Prdm15tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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