Clcf1 | cardiotrophin-like cytokine factor 1
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Hematopoietic system Skeleton Mortality/aging Cardiovascular system
14 No significant impact
5 Not tested
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:44Adult tissues
50Embryo tissues
increased bone mineral content | 1 supporting dataset | Clcf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.71x10-5 | ||
increased bone mineral density | 1 supporting dataset | Clcf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 7.8x10-6 | ||
prolonged QT interval | 1 supporting dataset | Clcf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.35x10-5 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Clcf1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
decreased leukocyte cell number | 1 supporting dataset | Clcf1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 8.62x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Clcf1em1(IMPC)J | homozygote | Early adult | N/A * |
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External links
No external links available for Clcf1.
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Clcf1em1(IMPC)J | Exon Deletion | | mouse |
Clcf1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Clcf1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Clcf1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |