Klk11 | kallikrein related-peptidase 11

GeneMGI:1929977Synonyms: Prss20, TLSP, +2 more

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Liver/biliary system Hematopoietic system Skeleton Craniofacial

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal testis morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal joint morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.2x10^-5
abnormal thymus morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal cranium morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.65x10^-5
abnormal liver morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Klk11^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klk11.

Associated images

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Histopathology

There is no histopathology data found for Klk11.

IMPC related publications

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External links

No external links available for Klk11.

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*Klk11^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Klk11^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell

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