Timm22 | translocase of inner mitochondrial membrane 22
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| increased circulating sodium level | 1 supporting dataset | Timm22tm1b(KOMP)Wtsi | heterozygote | Early adult | 9.85x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Timm22tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Timm22tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| hyperactivity | 6 supporting datasets | Timm22tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.7x10-10 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Timm22tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * |
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External links
No external links available for Timm22.
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| Timm22tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Timm22tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Timm22tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Timm22tm361548(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Timm22tm38113(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |