Asb1 | ankyrin repeat and SOCS box-containing 1

GeneMGI:1929735Synonyms: 1700054C17Rik, 1700029O08Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating potassium level	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.73x10^-6
enlarged spleen	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased CD4-positive NK T cell number	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.92x10^-5
enlarged thymus	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased circulating chloride level	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.53x10^-5
abnormal spleen morphology	1 supporting dataset	Asb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Asb1.

Associated images

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Histopathology

There is no histopathology data found for Asb1.

IMPC related publications

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External links

No external links available for Asb1.

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*Asb1^{em1(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse
*Asb1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Asb1^{tm373714(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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