Rec8 | REC8 meiotic recombination protein

GeneMGI:1929645Synonyms: Rec8L1, mrec

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

51Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating HDL cholesterol level	1 supporting dataset	Rec8^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.6x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Rec8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.25x10^-8
increased total body fat amount	1 supporting dataset	Rec8^{tm1b(KOMP)Wtsi}	homozygote	Late adult	2.4x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Rec8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.35x10^-9
male infertility	1 supporting dataset	Rec8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating cholesterol level	1 supporting dataset	Rec8^{tm1b(KOMP)Wtsi}	homozygote	Late adult	9.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rec8.

Associated images

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Histopathology

There is no histopathology data found for Rec8.

IMPC related publications

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External links

No external links available for Rec8.

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*Rec8^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Rec8^{tm1.1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	ES Cell
*Rec8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rec8^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rec8^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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