Prrg2 | proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

GeneMGI:1929596Synonyms: 1600014G02Rik, N4WBP1, +1 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

17 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating iron level1 supporting datasetPrrg2tm1b(EUCOMM)WtsihomozygoteEarly adult9.32x10-5 
increased circulating calcium level1 supporting datasetPrrg2tm1b(EUCOMM)WtsihomozygoteEarly adult4.86x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prrg2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Prrg2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Prrg2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Prrg2tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Prrg2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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