Cldn12 | claudin 12

GeneMGI:1929288

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes



increased grip strength	2 supporting datasets	Cldn12^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.39x10^-8
hyperactivity	1 supporting dataset	Cldn12^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.14x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cldn12.

Associated images

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Histopathology

There is no histopathology data found for Cldn12.

IMPC related publications

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External links

No external links available for Cldn12.

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*Cldn12^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Cldn12^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cldn12^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cldn12^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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