Ivd | isovaleryl coenzyme A dehydrogenase

GeneMGI:1929242Synonyms: 6720455E18Rik, 1300016K07Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetIvdtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal lens morphology1 supporting datasetIvdtm1b(EUCOMM)HmguheterozygoteEarly adult6.39x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ivdtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ivdtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Ivdtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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