Pus1 | pseudouridine synthase 1
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Behavior/neurological
13 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased grip strength | 1 supporting dataset | Pus1em1(IMPC)J | homozygote | Early adult | 5.78x10-5 | ||
| increased circulating bilirubin level | 1 supporting dataset | Pus1em1(IMPC)J | homozygote | Early adult | 3.31x10-5 | ||
| decreased grip strength | 2 supporting datasets | Pus1em1(IMPC)J | homozygote | Late adult | 1.35x10-5 | ||
| abnormal vocalization | 1 supporting dataset | Pus1em1(IMPC)J | homozygote | Early adult | 2.42x10-10 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Pus1em1(IMPC)J | homozygote | Early adult | 2.78x10-5 | ||
| increased circulating phosphate level | 1 supporting dataset | Pus1em1(IMPC)J | homozygote | Early adult | 2.24x10-5 | ||
| decreased locomotor activity | 1 supporting dataset | Pus1em1(IMPC)J | homozygote | Late adult | 1.78x10-6 |
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External links
No external links available for Pus1.
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| Pus1em1(IMPC)J | Exon Deletion | | mouse |
| Pus1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pus1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Pus1tm43391(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |