Rab2a | RAB2A, member RAS oncogene family
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Integument Embryo Growth/size/body region Hematopoietic system Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Rab2aem2(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Rab2aem2(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| increased red blood cell distribution width | 1 supporting dataset | Rab2aem2(IMPC)Tcp | heterozygote | Early adult | 3.11x10-32 | ||
| decreased erythrocyte cell number | 1 supporting dataset | Rab2aem2(IMPC)Tcp | heterozygote | Early adult | 1.52x10-6 | ||
| increased mean corpuscular volume | 1 supporting dataset | Rab2aem2(IMPC)Tcp | heterozygote | Early adult | 7.47x10-26 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Rab2aem2(IMPC)Tcp | heterozygote | Early adult | 6.07x10-10 | ||
| abnormal skin morphology | 2 supporting datasets | Rab2aem2(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| increased spleen weight | 1 supporting dataset | Rab2aem2(IMPC)Tcp | heterozygote | Early adult | 3.78x10-14 |
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External links
No external links available for Rab2a.
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| Rab2aem2(IMPC)Tcp | Exon Deletion | | mouse |
| Rab2atm168(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |