Fads3 | fatty acid desaturase 3

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

absent pinna reflex1 supporting datasetFads3tm1b(EUCOMM)HmguhomozygoteEarly adult1.8x10-8 
abnormal auditory brainstem response3 supporting datasetsFads3tm1b(EUCOMM)HmguhomozygoteEarly adult1.7x10-12 
decreased circulating phosphate level1 supporting datasetFads3tm1b(EUCOMM)HmguhomozygoteEarly adult8.89x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fads3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Fads3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Fads3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Fads3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Fads3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Fads3tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Fads3tm95251(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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