Mtor | mechanistic target of rapamycin kinase
GeneMGI:1928394Synonyms: FKBP-rapamycin-associated protein FRAP, mechanistic target of rapamycin (serine/threonine kinase), +5 more
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
18 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
6Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| increased circulating sodium level | 1 supporting dataset | Mtortm1a(EUCOMM)Wtsi | heterozygote | Early adult | 7.26x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Mtortm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Mtortm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.59x10-6 |
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External links
No external links available for Mtor.
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| Mtortm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Mtortm608(L1L2_gt0_Del_LacZ) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Mtortm608(pL1L2_GT0_DelLacZ_bsd) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |