Sirt2 | sirtuin 2
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Cardiovascular system
17 No significant impact
4 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
increased heart weight | 1 supporting dataset | Sirt2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 8.27x10-5 | ||
increased circulating creatinine level | 1 supporting dataset | Sirt2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 9.47x10-5 |
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External links
No external links available for Sirt2.
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Sirt2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Sirt2tm39885(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |