Scoc | short coiled-coil protein

GeneMGI:1927654Synonyms: short coiled-coil protein, 2810002J11Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging Cardiovascular system

16 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetScocem1(IMPC)JhomozygoteEarly adultN/A * 
decreased circulating calcium level1 supporting datasetScocem1(IMPC)JheterozygoteEarly adult1.33x10-14 
decreased heart rate1 supporting datasetScocem1(IMPC)JheterozygoteEarly adult1.16x10-5 
prolonged RR interval1 supporting datasetScocem1(IMPC)JheterozygoteEarly adult1.2x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scocem1(IMPC)JExon Deletionmouse
Scoctm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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