Dhx38 | DEAH-box helicase 38

GeneMGI:1927617Synonyms: Prp16, Ddx38, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Pigmentation Integument Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Dhx38^em1(IMPC)J	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Dhx38^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Dhx38^em1(IMPC)J	heterozygote	Early adult	4.2x10^-12
abnormal vocalization	1 supporting dataset	Dhx38^em1(IMPC)J	heterozygote	Early adult	2.94x10^-10
decreased hematocrit	1 supporting dataset	Dhx38^em1(IMPC)J	heterozygote	Early adult	4x10^-7
decreased erythrocyte cell number	1 supporting dataset	Dhx38^em1(IMPC)J	heterozygote	Early adult	4.84x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dhx38.

Associated images

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Histopathology

There is no histopathology data found for Dhx38.

IMPC related publications

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External links

No external links available for Dhx38.

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*Dhx38^em1(IMPC)J*	Exon Deletion	‌	mouse
*Dhx38^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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