Smarce1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1

GeneMGI:1927347Synonyms: 9030408N19Rik, 5830412H02Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular volume1 supporting datasetSmarce1em1(IMPC)JheterozygoteEarly adult6.02x10-8 
decreased mean corpuscular hemoglobin1 supporting datasetSmarce1em1(IMPC)JheterozygoteEarly adult2.11x10-10 
preweaning lethality, complete penetrance1 supporting datasetSmarce1em1(IMPC)JhomozygoteEarly adultN/A * 
decreased locomotor activity1 supporting datasetSmarce1em1(IMPC)JheterozygoteEarly adult2.25x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Smarce1em1(IMPC)JExon Deletionmouse
Smarce1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Smarce1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Smarce1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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