Pals2 | protein associated with LIN7 2, MAGUK family member

GeneMGI:1927340Synonyms: Mpp6, P55t, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Adipose tissue Growth/size/body region Digestive/alimentary Limbs/digits/tail Hematopoietic system Skeleton

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

fusion of vertebral arches1 supporting datasetPals2em1(IMPC)RbrchomozygoteEarly adult4.49x10-5 
increased total body fat amount2 supporting datasetsPals2em1(IMPC)RbrchomozygoteEarly adult4.3x10-5 
decreased body length1 supporting datasetPals2em1(IMPC)RbrchomozygoteEarly adult1.47x10-7 
short tibia1 supporting datasetPals2em1(IMPC)RbrchomozygoteEarly adult1.09x10-21 
abnormal bone structure1 supporting datasetPals2em1(IMPC)RbrchomozygoteEarly adult8.51x10-8 
abnormal stomach morphology1 supporting datasetPals2em1(IMPC)RbrchomozygoteEarly adultN/A * 
decreased bone mineral content2 supporting datasetsPals2em1(IMPC)RbrchomozygoteEarly adult2.74x10-7 
abnormal spleen morphology1 supporting datasetPals2em1(IMPC)RbrchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Pals2em1(IMPC)RbrcExon Deletionmouse
Pals2em2(IMPC)RbrcExon Deletionmouse
Pals2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Pals2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter