Cgn | cingulin

GeneMGI:1927237Synonyms: 6330408J11Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Cardiovascular system Mortality/aging

13 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
43Embryo tissues

Phenotypes

abnormal forebrain morphology1 supporting datasetCgntm1b(KOMP)WtsihomozygoteE12.5N/A * 
abnormal embryo size1 supporting datasetCgntm1b(KOMP)WtsihomozygoteE18.5N/A * 
hemorrhage1 supporting datasetCgntm1b(KOMP)WtsihomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetCgntm1b(KOMP)WtsihomozygoteEarly adultN/A * 
cyanosis1 supporting datasetCgntm1b(KOMP)WtsihomozygoteE18.5N/A * 
abnormal tail morphology1 supporting datasetCgntm1b(KOMP)WtsihomozygoteE18.5N/A * 
abnormal neural tube closure1 supporting datasetCgntm1b(KOMP)WtsihomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cgntm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cgntm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cgntm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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