Chp1 | calcineurin-like EF hand protein 1

GeneMGI:1927185Synonyms: 1500003O03Rik, vac, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Hematopoietic system Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Chp1^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Chp1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Chp1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Chp1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Chp1^em1(IMPC)Tcp	heterozygote	Early adult	6.02x10^-6
embryonic lethality prior to tooth bud stage	1 supporting dataset	Chp1^em1(IMPC)Tcp	homozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Chp1^em1(IMPC)Tcp	heterozygote	E9.5	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Chp1^em1(IMPC)Tcp	heterozygote	Early adult	8.76x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Chp1^em1(IMPC)Tcp	heterozygote	Early adult	8.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chp1.

Associated images

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Histopathology

There is no histopathology data found for Chp1.

IMPC related publications

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External links

No external links available for Chp1.

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*Chp1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Chp1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Chp1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Chp1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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