B4galt5 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Embryo Growth/size/body region Mortality/aging
13 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
embryonic growth retardation | 1 supporting dataset | B4galt5em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | B4galt5em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
increased circulating alanine transaminase level | 1 supporting dataset | B4galt5em1(IMPC)Tcp | heterozygote | Early adult | 2.72x10-7 | ||
abnormal skin morphology | 1 supporting dataset | B4galt5em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | B4galt5em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
enlarged lymph nodes | 1 supporting dataset | B4galt5em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | B4galt5em1(IMPC)Tcp | heterozygote | E9.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | B4galt5em1(IMPC)Tcp | heterozygote | E9.5 | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | B4galt5em1(IMPC)Tcp | homozygote | E12.5 | N/A * |
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External links
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B4galt5em1(IMPC)Tcp | Exon Deletion | | mouse |
B4galt5tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
B4galt5tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |