Clptm1 | cleft lip and palate associated transmembrane protein 1

GeneMGI:1927155Synonyms: N14, HS9

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Integument Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



enlarged lymph nodes	1 supporting dataset	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased locomotor activity	2 supporting datasets	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	3.97x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Clptm1^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Clptm1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	3.66x10^-12
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	5.16x10^-5
decreased exploration in new environment	1 supporting dataset	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	6.82x10^-15
increased monocyte cell number	2 supporting datasets	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	4.38x10^-14
decreased mean corpuscular hemoglobin	1 supporting dataset	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	1.6x10^-6
abnormal skin morphology	1 supporting dataset	Clptm1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clptm1.

Associated images

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Histopathology

There is no histopathology data found for Clptm1.

IMPC related publications

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External links

No external links available for Clptm1.

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*Clptm1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Clptm1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Clptm1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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