Slc5a7 | solute carrier family 5 (choline transporter), member 7

GeneMGI:1927126Synonyms: CHT1

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Adipose tissue Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased grip strength	2 supporting datasets	Slc5a7^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.08x10^-13
decreased circulating fructosamine level	1 supporting dataset	Slc5a7^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	3.88x10^-5
abnormal hair growth	1 supporting dataset	Slc5a7^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	9.86x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Slc5a7^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased total body fat amount	1 supporting dataset	Slc5a7^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	3.43x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc5a7.

Associated images

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Histopathology

There is no histopathology data found for Slc5a7.

IMPC related publications

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External links

No external links available for Slc5a7.

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*Slc5a7^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc5a7^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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