Tmem131 | transmembrane protein 131

GeneMGI:1927110Synonyms: Neg, CC28, +4 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Embryo Growth/size/body region Behavior/neurological Craniofacial Mortality/aging Cardiovascular system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Tmem131^em1(IMPC)J	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Tmem131^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Tmem131^em1(IMPC)J	heterozygote	Early adult	5.8x10^-5
abnormal vocalization	1 supporting dataset	Tmem131^em1(IMPC)J	heterozygote	Early adult	9.24x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Tmem131^em1(IMPC)J	heterozygote	Early adult	1.99x10^-6
edema	1 supporting dataset	Tmem131^em1(IMPC)J	homozygote	E15.5	N/A ^*
hemorrhage	1 supporting dataset	Tmem131^em1(IMPC)J	homozygote	E15.5	N/A ^*
decreased grip strength	1 supporting dataset	Tmem131^em1(IMPC)J	heterozygote	Early adult	1.94x10^-5
abnormal craniofacial morphology	1 supporting dataset	Tmem131^em1(IMPC)J	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem131.

Associated images

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Histopathology

There is no histopathology data found for Tmem131.

IMPC related publications

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External links

No external links available for Tmem131.

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*Tmem131^em1(IMPC)J*	Exon Deletion	‌	mouse
*Tmem131^{em1(IMPC)Wtsi}*	Exon Deletion	‌	mouse

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