Irgm2 | immunity-related GTPase family M member 2

GeneMGI:1926262Synonyms: Gtpi, Iigp2

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Vision/eye Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat appearance1 supporting datasetIrgm2em1(IMPC)JhomozygoteLate adult6.29x10-7 
absent vibrissae1 supporting datasetIrgm2em1(IMPC)JhomozygoteLate adult2.31x10-6 
decreased circulating serum albumin level1 supporting datasetIrgm2em1(IMPC)JhomozygoteLate adult1.11x10-5 
abnormal startle reflex1 supporting datasetIrgm2em1(IMPC)JhomozygoteLate adult9.56x10-6 
decreased thigmotaxis4 supporting datasetsIrgm2em1(IMPC)JhomozygoteEarly adult2.15x10-10 
abnormal lens morphology1 supporting datasetIrgm2em1(IMPC)JhomozygoteLate adult2.98x10-5 
abnormal skin morphology1 supporting datasetIrgm2em1(IMPC)JhomozygoteLate adult1.53x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Irgm2em1(IMPC)JIntra-exon deletionmouse
Irgm2tm236839(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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