Ube2j1 | ubiquitin-conjugating enzyme E2J 1

GeneMGI:1926245Synonyms: 0710008M05Rik, Ubc6p, +2 more

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Limbs/digits/tail Behavior/neurological Skeleton

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:152Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating cholesterol level	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	2.28x10^-5
male infertility	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	1.63x10^-5
increased circulating amylase level	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	7.52x10^-5
decreased bone mineral content	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	1.38x10^-6
decreased lean body mass	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	3.14x10^-5
short tibia	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	4.03x10^-5
increased fluid intake	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	1.03x10^-5
decreased bone mineral density	1 supporting dataset	Ube2j1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	2.5x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ube2j1.

Associated images

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Histopathology

There is no histopathology data found for Ube2j1.

IMPC related publications

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External links

No external links available for Ube2j1.

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*Ube2j1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Ube2j1^{tm1.1(NCOM)Mfgc}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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