Tnip1 | TNFAIP3 interacting protein 1

GeneMGI:1926194Synonyms: ABIN1, Nef, +2 more

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:25Significant phenotypes

1Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased circulating serum albumin level	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.13x10^-11
decreased lymphocyte cell number	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.43x10^-8
increased red blood cell distribution width	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.27x10^-35
decreased erythrocyte cell number	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.08x10^-30
increased basophil cell number	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.81x10^-7
increased circulating alanine transaminase level	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.32x10^-88
increased large unstained cell number	2 supporting datasets	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.3x10^-18
increased freezing behavior	2 supporting datasets	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.68x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.75x10^-31
increased mean platelet volume	1 supporting dataset	Tnip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.9x10^-49

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tnip1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tnip1.

IMPC related publications

Loading...

External links

No external links available for Tnip1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tnip1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Tnip1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tnip1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tnip1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Tnip1^{tm33632(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes