Chsy3 | chondroitin sulfate synthase 3

GeneMGI:1926173Synonyms: 4833446K15Rik

Physiological systems

18 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Integument Adipose tissue Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

9 No significant impact

6 Not tested

Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adult3.27x10-5 
abnormal eye morphology1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adultN/A * 
decreased total body fat amount1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adult4.16x10-5 
decreased body length1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adult2.37x10-17 
abnormal skin morphology1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adultN/A * 
female infertility1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adultN/A * 
increased lean body mass1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adult7.59x10-11 
increased mean platelet volume1 supporting datasetChsy3em2(IMPC)MbphomozygoteEarly adult1.48x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Chsy3em2(IMPC)MbpExon Deletionmouse

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