Mdn1 | midasin AAA ATPase 1

GeneMGI:1926159Synonyms: LOC213784, 4833432B22Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

18 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating aspartate transaminase level1 supporting datasetMdn1tm1a(KOMP)WtsiheterozygoteEarly adult1.03x10-10 
increased lactate dehydrogenase level1 supporting datasetMdn1tm1a(KOMP)WtsiheterozygoteEarly adult7.93x10-23 
increased circulating alanine transaminase level1 supporting datasetMdn1tm1a(KOMP)WtsiheterozygoteEarly adult2.61x10-13 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mdn1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mdn1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Mdn1tm300173(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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