Crispld2 | cysteine-rich secretory protein LCCL domain containing 2
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Skeleton Mortality/aging Cardiovascular system
13 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:43Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Crispld2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Crispld2tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Crispld2tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * | ||
| decreased circulating triglyceride level | 1 supporting dataset | Crispld2tm1.1(KOMP)Vlcg | heterozygote | Early adult | 8.52x10-9 | ||
| decreased bone mineral density | 1 supporting dataset | Crispld2tm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.71x10-7 | ||
| abnormal embryo size | 1 supporting dataset | Crispld2tm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * |
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External links
No external links available for Crispld2.
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| Crispld2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Crispld2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Crispld2tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Crispld2tm43718(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |