Zfp536 | zinc finger protein 536

GeneMGI:1926102Synonyms: 9630010P11Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Respiratory system Hematopoietic system Behavior/neurological Mortality/aging

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hyperactivity	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	2.13x10^-5
cyanosis	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
respiratory system phenotype	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	homozygote	E18.5	N/A ^*
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	2.74x10^-6
increased circulating chloride level	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	5.17x10^-5
increased hemoglobin content	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	2.37x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Zfp536^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zfp536.

Associated images

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Histopathology

There is no histopathology data found for Zfp536.

IMPC related publications

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External links

No external links available for Zfp536.

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*Zfp536^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Zfp536^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Zfp536^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zfp536^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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