Stxbp5 | syntaxin binding protein 5 (tomosyn)

GeneMGI:1926058Synonyms: 0710001E20Rik, 4930565N16Rik, +2 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Behavior/neurological Skeleton Mortality/aging Renal/urinary system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal kidney morphology	1 supporting dataset	Stxbp5^{em1(IMPC)Hmgu}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Stxbp5^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Stxbp5^{em1(IMPC)Hmgu}	heterozygote	Early adult	2.17x10^-10
abnormal gait	1 supporting dataset	Stxbp5^{em1(IMPC)Hmgu}	heterozygote	Early adult	8.11x10^-5
increased bone mineral content	1 supporting dataset	Stxbp5^{em1(IMPC)Hmgu}	heterozygote	Early adult	3.78x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stxbp5.

Associated images

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Histopathology

There is no histopathology data found for Stxbp5.

IMPC related publications

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External links

No external links available for Stxbp5.

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*Stxbp5^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse

My Genes