Eml4 | echinoderm microtubule associated protein like 4

GeneMGI:1926048Synonyms: 4930443C24Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Behavior/neurological Mortality/aging Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

prolonged PR interval1 supporting datasetEml4em1(IMPC)JheterozygoteEarly adult7.72x10-5 
abnormal vocalization1 supporting datasetEml4em1(IMPC)JheterozygoteEarly adult6.79x10-8 
preweaning lethality, incomplete penetrance1 supporting datasetEml4em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal coat/hair pigmentation1 supporting datasetEml4em1(IMPC)JheterozygoteEarly adult2.71x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eml4em1(IMPC)JExon Deletionmouse
Eml4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Eml4tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Eml4tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Eml4tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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