Usp54 | ubiquitin specific peptidase 54

GeneMGI:1926037Synonyms: 4930429G18Rik, C030002J06Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased circulating aspartate transaminase level	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.72x10^-7
enlarged heart	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased lymphocyte cell number	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.25x10^-19
decreased hemoglobin content	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.39x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.54x10^-7
decreased circulating amylase level	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.77x10^-5
increased neutrophil cell number	2 supporting datasets	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.78x10^-21
decreased exploration in new environment	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.58x10^-5
decreased circulating total protein level	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.14x10^-5
increased red blood cell distribution width	1 supporting dataset	Usp54^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.51x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Usp54.

Associated images

Loading...

Histopathology

There is no histopathology data found for Usp54.

IMPC related publications

Loading...

External links

No external links available for Usp54.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Usp54^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Usp54^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes