Pus7 | pseudouridylate synthase 7

GeneMGI:1925947Synonyms: C330017I15Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetPus7em1(IMPC)JhomozygoteEarly adultN/A * 
decreased circulating glucose level1 supporting datasetPus7em1(IMPC)JheterozygoteEarly adult1.21x10-5 
abnormal placenta size1 supporting datasetPus7em1(IMPC)JhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pus7em1(IMPC)JExon Deletionmouse
Pus7tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pus7tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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