Nol3 | nucleolar protein 3 (apoptosis repressor with CARD domain)

GeneMGI:1925938Synonyms: Nop30, B430311C09Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



enlarged lymph nodes	2 supporting datasets	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
cataract	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	1.77x10^-6
small kidney	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	2.89x10^-8
abnormal kidney morphology	2 supporting datasets	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small spleen	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal ovary morphology	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged ovary	1 supporting dataset	Nol3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nol3.

Associated images

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Histopathology

There is no histopathology data found for Nol3.

IMPC related publications

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External links

No external links available for Nol3.

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*Nol3^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Nol3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nol3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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