Fhod3 | formin homology 2 domain containing 3

GeneMGI:1925847Synonyms: A930009H06Rik

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Embryo Growth/size/body region Nervous system Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

15 No significant impact

2 Not tested

Gene metrics:14Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal neural tube morphology1 supporting datasetFhod3em1(IMPC)MbpheterozygoteE9.5N/A * 
decreased exploration in new environment1 supporting datasetFhod3em1(IMPC)MbpheterozygoteEarly adult8.9x10-5 
abnormal neural tube closure1 supporting datasetFhod3em1(IMPC)MbphomozygoteE9.5N/A * 
embryonic growth retardation1 supporting datasetFhod3em1(IMPC)MbphomozygoteE9.5N/A * 
abnormal neural tube morphology1 supporting datasetFhod3em1(IMPC)MbphomozygoteE9.5N/A * 
abnormal neural tube closure1 supporting datasetFhod3em1(IMPC)MbpheterozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsFhod3em1(IMPC)MbphomozygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetFhod3em1(IMPC)MbpheterozygoteEarly adult4.44x10-5 
abnormal placenta vasculature1 supporting datasetFhod3em1(IMPC)MbpheterozygoteE15.5N/A * 
abnormal forebrain development1 supporting datasetFhod3em1(IMPC)MbphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fhod3em1(IMPC)MbpExon Deletionmouse

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