Srbd1 | S1 RNA binding domain 1

GeneMGI:1925836Synonyms: D530025C17Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Pigmentation Integument Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation1 supporting datasetSrbd1em1(IMPC)JheterozygoteLate adult3.11x10-5 
impaired righting response1 supporting datasetSrbd1em1(IMPC)JheterozygoteLate adult2.36x10-7 
embryonic lethality prior to organogenesis1 supporting datasetSrbd1em1(IMPC)JhomozygoteE9.5N/A * 
limb grasping1 supporting datasetSrbd1em1(IMPC)JheterozygoteLate adult6.81x10-8 
increased grip strength1 supporting datasetSrbd1em1(IMPC)JheterozygoteLate adult1.97x10-6 
preweaning lethality, complete penetrance1 supporting datasetSrbd1em1(IMPC)JhomozygoteEarly adultN/A * 
increased exploration in new environment1 supporting datasetSrbd1em1(IMPC)JheterozygoteLate adult9.29x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Srbd1em1(IMPC)JExon Deletionmouse
Srbd1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Srbd1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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