Cul9 | cullin 9

GeneMGI:1925559Synonyms: 1810035I07Rik, Parc

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal vertebral arch morphology2 supporting datasetsCul9em1(IMPC)CcpczhomozygoteEarly adult1.44x10-6 
increased circulating creatine kinase level1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adult1.02x10-14 
abnormal vertebrae morphology1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adult2.11x10-5 
increased circulating lactate dehydrogenase level1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adult8.61x10-6 
increased circulating potassium level1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adult1.85x10-7 
abnormal spleen morphology1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased blood urea nitrogen level1 supporting datasetCul9em1(IMPC)CcpczhomozygoteEarly adult4.81x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cul9em1(IMPC)CcpczExon Deletionmouse

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