Sbf1 | SET binding factor 1

GeneMGI:1925230Synonyms: 2610510A08Rik, B230113C15Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

8 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:24Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased brain size	2 supporting datasets	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal brain morphology	2 supporting datasets	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	4 supporting datasets	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	2.42x10^-10
decreased lymphocyte cell number	1 supporting dataset	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	6.85x10^-5
small liver	1 supporting dataset	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased grip strength	2 supporting datasets	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	5.5x10^-5
increased bone mineral content	1 supporting dataset	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	7.99x10^-7
decreased fasting circulating glucose level	1 supporting dataset	Sbf1^em1(IMPC)Mbp	homozygote	Early adult	3.29x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Sbf1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Sbf1.

IMPC related publications

Loading...

External links

No external links available for Sbf1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Sbf1^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Sbf1^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

My Genes