Tmem50b | transmembrane protein 50B

GeneMGI:1925225Synonyms: B230114J08Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	2 supporting datasets	Tmem50b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.32x10^-6
abnormal vitreous body morphology	1 supporting dataset	Tmem50b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.19x10^-6
increased cornea thickness	1 supporting dataset	Tmem50b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.38x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem50b.

Associated images

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Histopathology

There is no histopathology data found for Tmem50b.

IMPC related publications

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External links

No external links available for Tmem50b.

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*Tmem50b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Tmem50b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tmem50b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmem50b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Tmem50b^{tm40880(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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