Krtap17-1 | keratin associated protein 17-1

GeneMGI:1925164Synonyms: A030006P16Rik

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Adipose tissue Growth/size/body region Behavior/neurological Skeleton Renal/urinary system

14 No significant impact

3 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased kidney weight1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult8.15x10-8 
increased lean body mass1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult1.51x10-5 
thick skin1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal coat/ hair morphology3 supporting datasetsKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult1.19x10-17 
decreased locomotor activity5 supporting datasetsKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult3.5x10-12 
decreased total body fat amount1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult4.87x10-6 
decreased circulating HDL cholesterol level1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult9.92x10-6 
decreased bone mineral density1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adult8.62x10-7 
scaly skin1 supporting datasetKrtap17-1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Krtap17-1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Krtap17-1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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