Tchp | trichoplein, keratin filament binding

GeneMGI:1925082Synonyms: A930031F18Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Skeleton Craniofacial

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating HDL cholesterol level	1 supporting dataset	Tchp^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.16x10^-10
abnormal incisor morphology	1 supporting dataset	Tchp^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.55x10^-5
increased circulating LDL cholesterol level	1 supporting dataset	Tchp^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.35x10^-11
increased circulating cholesterol level	1 supporting dataset	Tchp^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.61x10^-15

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tchp.

Associated images

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Histopathology

There is no histopathology data found for Tchp.

IMPC related publications

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External links

No external links available for Tchp.

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*Tchp^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tchp^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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