Gramd1b | GRAM domain containing 1B

GeneMGI:1925037Synonyms: A930008A22Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Nervous system Behavior/neurological Mortality/aging Craniofacial

13 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal head shape1 supporting datasetGramd1bem1(IMPC)JhomozygoteE18.5N/A * 
exencephaly1 supporting datasetGramd1bem1(IMPC)JhomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance1 supporting datasetGramd1bem1(IMPC)JhomozygoteEarly adultN/A * 
unresponsive to tactile stimuli1 supporting datasetGramd1bem1(IMPC)JhomozygoteE18.5N/A * 
abnormal tail morphology1 supporting datasetGramd1bem1(IMPC)JhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gramd1bem1(IMPC)JExon Deletionmouse
Gramd1btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Gramd1btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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