Elp4 | elongator acetyltransferase complex subunit 4

GeneMGI:1925016Synonyms: Paxneb, A330107A17Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Elp4^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Elp4^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Elp4^em1(IMPC)Tcp	heterozygote	Early adult	8.41x10^-5
increased vertical activity	1 supporting dataset	Elp4^em1(IMPC)Tcp	heterozygote	Early adult	2.81x10^-7
abnormal retina blood vessel morphology	1 supporting dataset	Elp4^em1(IMPC)Tcp	heterozygote	Early adult	9.39x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Elp4^em1(IMPC)Tcp	heterozygote	Early adult	7.84x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Elp4.

Associated images

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Histopathology

There is no histopathology data found for Elp4.

IMPC related publications

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External links

No external links available for Elp4.

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*Elp4^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Elp4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Elp4^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Elp4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Elp4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Elp4^{tm40231(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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