Adgrf1 | adhesion G protein-coupled receptor F1

GeneMGI:1924846Synonyms: Gpr110, 5031409J19Rik

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetAdgrf1em1(IMPC)CcpczhomozygoteEarly adult2.07x10-5 
abnormal spleen morphology1 supporting datasetAdgrf1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetAdgrf1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetAdgrf1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal retina vasculature morphology1 supporting datasetAdgrf1em1(IMPC)CcpczhomozygoteEarly adult3.73x10-6 
enlarged heart1 supporting datasetAdgrf1em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Adgrf1em1(IMPC)CcpczExon Deletionmouse
Adgrf1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Adgrf1tm43780(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Adgrf1tm43780(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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