Ppfia1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

GeneMGI:1924750Synonyms: Liprin-alpha1, C030014K08Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Pigmentation Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Ppfia1^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Ppfia1^em1(IMPC)J	heterozygote	Early adult	4.2x10^-12
abnormal embryo size	1 supporting dataset	Ppfia1^em1(IMPC)J	homozygote	E18.5	N/A ^*
abnormal vocalization	1 supporting dataset	Ppfia1^em1(IMPC)J	heterozygote	Early adult	2.94x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppfia1.

Associated images

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Histopathology

There is no histopathology data found for Ppfia1.

IMPC related publications

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External links

No external links available for Ppfia1.

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*Ppfia1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Ppfia1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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