Actr5 | ARP5 actin-related protein 5
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Nervous system Behavior/neurological Mortality/aging
15 No significant impact
4 Not tested
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues
increased exploration in new environment | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 1.61x10-6 | ||
abnormal embryo size | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Actr5tm2b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
abnormal hindbrain development | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
abnormal midbrain development | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
abnormal embryo turning | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
abnormal forebrain development | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Actr5tm2b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * |
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External links
No external links available for Actr5.
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Actr5tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Actr5tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Actr5tm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |