Lyz3 | lysozyme 3

GeneMGI:1924647Synonyms: 9530003J23Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Nervous system Skeleton

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alanine transaminase level	1 supporting dataset	Lyz3^{tm1(KOMP)Vlcg}	homozygote	Early adult	2.69x10^-11
increased circulating aspartate transaminase level	1 supporting dataset	Lyz3^{tm1(KOMP)Vlcg}	homozygote	Early adult	5.86x10^-7
decreased bone mineral density	1 supporting dataset	Lyz3^{tm1(KOMP)Vlcg}	homozygote	Early adult	9.55x10^-6
decreased prepulse inhibition	1 supporting dataset	Lyz3^{tm1(KOMP)Vlcg}	homozygote	Early adult	3.68x10^-5
increased body length	1 supporting dataset	Lyz3^{tm1(KOMP)Vlcg}	homozygote	Early adult	2.47x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lyz3.

Associated images

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Histopathology

There is no histopathology data found for Lyz3.

IMPC related publications

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External links

No external links available for Lyz3.

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*Lyz3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Lyz3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Lyz3^{tm106188(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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